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How long does compounded semaglutide last in the fridge

You are looking into lower-dose or compounded routes.

Reference and calculator, not medical advice. Dosing figures below are transcribed from FDA-approved prescribing information and link back to it. Last reviewed August 2026.

There is no universal answer to this, and that is itself the important part. A compounded preparation's beyond-use date and storage conditions are set by the pharmacy that made it, and they are printed on the label of your vial — not published in a document you can look up. Two compounded semaglutide vials from different pharmacies can carry genuinely different dates and different storage instructions, so a number someone quotes from their own vial does not transfer to yours.

What the approved products publish, by contrast, is specific: each manufacturer's labelling states its own refrigeration range, how long a pen may be kept at room temperature once in use, and when it must be discarded. Those figures belong to that product and are not a template for a compounded vial, because the formulation, the preservative and the container are all different. If your vial's label is missing this, the pharmacy that dispensed it is the only source that can answer — not a forum thread about someone else's vial.

Compounded vs brand-name: what actually differs

Current as of August 2026.

Compounded is usually cheaper but can change with the rules; brand-name costs more and is more predictable. Worth raising with whoever writes your prescription. FDA’s compounding pages have the detail if you want it.

Side-by-side

Structural facts from each product’s prescribing information.

ProductActive ingredientIndicationFrequencyStartMax labelledSteps to max
Zepbound
Eli Lilly		TirzepatideWeight managementWeekly2.5 mg15 mg6
Mounjaro
Eli Lilly		TirzepatideType 2 diabetesWeekly2.5 mg15 mg6
Wegovy
Novo Nordisk		SemaglutideWeight managementWeekly0.25 mg2.4 mg5
Ozempic
Novo Nordisk		SemaglutideType 2 diabetesWeekly0.25 mg2 mg4
Saxenda
Novo Nordisk		LiraglutideWeight managementDaily0.6 mg3 mg5
Trulicity
Eli Lilly		DulaglutideType 2 diabetesWeekly0.75 mg4.5 mg4

mg → syringe units converter

U-100 syringe. Formula: (dose ÷ concentration) × 100.

12.5units on a U-100 syringe
= 0.125 mL  ·  2.5 mg at 20 mg/mL

Check the concentration printed on the vial you are actually holding. The same dose in milligrams is a completely different mark on the syringe at a different concentration. If the number here does not match what your prescriber told you, trust your prescriber.

Where a compounded product is lawfully supplied, it may come at a concentration that differs from the branded pens — and that is precisely where the milligram-to-units arithmetic goes wrong. Convert using the concentration printed on the vial you are holding, never a figure from a forum post.

Common questions

Is microdosing an approved dosing strategy?
No. It is not a labelled regimen. The prescribing information defines a stepped schedule with a specified starting dose; anything below that is off-label and a decision for a prescriber.

Sources and last review

Every dosing figure on this page is transcribed from an FDA-approved label and links back to it. Conversions are arithmetic you can repeat by hand. Nothing here is reviewed by a clinician, and this site does not employ one — which is exactly why what I do publish stays traceable to its source.

Transcribed from the labels above and checked by me — Gavin, who builds this site, takes a GLP-1, and is not a clinician. Last reviewed August 2026. Found an error? [email protected] — I treat corrections as bugs. How this site is built and funded.

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